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1.

Genetic diversity fuels gene discovery for tobacco and alcohol use.

Saunders, Gretchen R B; Wang, Xingyan; Chen, Fang; Jang, Seon-Kyeong; Liu, Mengzhen; Wang, Chen; Gao, Shuang; Jiang, Yu; Khunsriraksakul, Chachrit; Otto, Jacqueline M; Addison, Clifton; Akiyama, Masato; Albert, Christine M; Aliev, Fazil; Alonso, Alvaro; Arnett, Donna K; Ashley-Koch, Allison E; Ashrani, Aneel A; Barnes, Kathleen C; Barr, R Graham; Bartz, Traci M; Becker, Diane M; Bielak, Lawrence F; Benjamin, Emelia J; Bis, Joshua C; Bjornsdottir, Gyda; Blangero, John; Bleecker, Eugene R; Boardman, Jason D; Boerwinkle, Eric; Boomsma, Dorret I; Boorgula, Meher Preethi; Bowden, Donald W; Brody, Jennifer A; Cade, Brian E; Chasman, Daniel I; Chavan, Sameer; Chen, Yii-Der Ida; Chen, Zhengming; Cheng, Iona; Cho, Michael H; Choquet, Hélène; Cole, John W; Cornelis, Marilyn C; Cucca, Francesco; Curran, Joanne E; de Andrade, Mariza; Dick, Danielle M; Docherty, Anna R; Duggirala, Ravindranath.

Nature ; 612(7941): 720-724, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36477530

2.

Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study.

Wang, Yuxuan; Selvaraj, Margaret Sunitha; Li, Xihao; Li, Zilin; Holdcraft, Jacob A; Arnett, Donna K; Bis, Joshua C; Blangero, John; Boerwinkle, Eric; Bowden, Donald W; Cade, Brian E; Carlson, Jenna C; Carson, April P; Chen, Yii-Der Ida; Curran, Joanne E; de Vries, Paul S; Dutcher, Susan K; Ellinor, Patrick T; Floyd, James S; Fornage, Myriam; Freedman, Barry I; Gabriel, Stacey; Germer, Soren; Gibbs, Richard A; Guo, Xiuqing; He, Jiang; Heard-Costa, Nancy; Hildalgo, Bertha; Hou, Lifang; Irvin, Marguerite R; Joehanes, Roby; Kaplan, Robert C; Kardia, Sharon Lr; Kelly, Tanika N; Kim, Ryan; Kooperberg, Charles; Kral, Brian G; Levy, Daniel; Li, Changwei; Liu, Chunyu; Lloyd-Jone, Don; Loos, Ruth Jf; Mahaney, Michael C; Martin, Lisa W; Mathias, Rasika A; Minster, Ryan L; Mitchell, Braxton D; Montasser, May E; Morrison, Alanna C; Murabito, Joanne M.

Am J Hum Genet ; 110(10): 1704-1717, 2023 10 05.

Artículo en Inglés | MEDLINE | ID: mdl-37802043

3.

A genetic association study of circulating coagulation Factor VIII and von Willebrand Factor levels.

de Vries, Paul S; Reventun, Paula; Brown, Michael R; Heath, Adam S; Huffman, Jennifer E; Le, Ngoc-Quynh; Bebo, Allison; Brody, Jennifer A; Temprano-Sagrera, Gerard; Raffield, Laura M; Ozel, Ayse Bilge; Thibord, Florian; Jain, Deepti; Lewis, Joshua P; Rodriguez, Benjamin A T; Pankratz, Nathan; Taylor, Kent D; Polasek, Ozren; Chen, Ming-Huei; Yanek, Lisa R; Carrasquilla, German D; Marioni, Riccardo; Kleber, Marcus E; Trégouët, David-Alexandre; Yao, Jie; Li-Gao, Ruifang; Joshi, Peter K; Trompet, Stella; Martinez-Perez, Angel; Ghanbari, Mohsen; Howard, Tom E; Reiner, Alex P; Arvanitis, Marios; Ryan, Kathleen A; Bartz, Traci M; Rudan, Igor; Faraday, Nauder; Linneberg, Allan; Ekunwe, Lynette; Davies, Gail; Delgado, Graciela E; Suchon, Pierre; Guo, Xiuqing; Rosendaal, Frits R; Klaric, Lucija; Noordam, Raymond; van Rooij, Frank; Curran, Joanne E; Wheeler, Marsha M; Osburn, William O.

Blood ; 2024 02 06.

Artículo en Inglés | MEDLINE | ID: mdl-38320121

4.

Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.

Hindy, George; Dornbos, Peter; Chaffin, Mark D; Liu, Dajiang J; Wang, Minxian; Selvaraj, Margaret Sunitha; Zhang, David; Park, Joseph; Aguilar-Salinas, Carlos A; Antonacci-Fulton, Lucinda; Ardissino, Diego; Arnett, Donna K; Aslibekyan, Stella; Atzmon, Gil; Ballantyne, Christie M; Barajas-Olmos, Francisco; Barzilai, Nir; Becker, Lewis C; Bielak, Lawrence F; Bis, Joshua C; Blangero, John; Boerwinkle, Eric; Bonnycastle, Lori L; Bottinger, Erwin; Bowden, Donald W; Bown, Matthew J; Brody, Jennifer A; Broome, Jai G; Burtt, Noël P; Cade, Brian E; Centeno-Cruz, Federico; Chan, Edmund; Chang, Yi-Cheng; Chen, Yii-Der I; Cheng, Ching-Yu; Choi, Won Jung; Chowdhury, Rajiv; Contreras-Cubas, Cecilia; Córdova, Emilio J; Correa, Adolfo; Cupples, L Adrienne; Curran, Joanne E; Danesh, John; de Vries, Paul S; DeFronzo, Ralph A; Doddapaneni, Harsha; Duggirala, Ravindranath; Dutcher, Susan K; Ellinor, Patrick T; Emery, Leslie S.

Am J Hum Genet ; 109(1): 81-96, 2022 01 06.

Artículo en Inglés | MEDLINE | ID: mdl-34932938

5.

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.

Li, Zilin; Li, Xihao; Zhou, Hufeng; Gaynor, Sheila M; Selvaraj, Margaret Sunitha; Arapoglou, Theodore; Quick, Corbin; Liu, Yaowu; Chen, Han; Sun, Ryan; Dey, Rounak; Arnett, Donna K; Auer, Paul L; Bielak, Lawrence F; Bis, Joshua C; Blackwell, Thomas W; Blangero, John; Boerwinkle, Eric; Bowden, Donald W; Brody, Jennifer A; Cade, Brian E; Conomos, Matthew P; Correa, Adolfo; Cupples, L Adrienne; Curran, Joanne E; de Vries, Paul S; Duggirala, Ravindranath; Franceschini, Nora; Freedman, Barry I; Göring, Harald H H; Guo, Xiuqing; Kalyani, Rita R; Kooperberg, Charles; Kral, Brian G; Lange, Leslie A; Lin, Bridget M; Manichaikul, Ani; Manning, Alisa K; Martin, Lisa W; Mathias, Rasika A; Meigs, James B; Mitchell, Braxton D; Montasser, May E; Morrison, Alanna C; Naseri, Take; O'Connell, Jeffrey R; Palmer, Nicholette D; Peyser, Patricia A; Psaty, Bruce M; Raffield, Laura M.

Nat Methods ; 19(12): 1599-1611, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36303018

6.

Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative.

Little, Amarise; Hu, Yao; Sun, Quan; Jain, Deepti; Broome, Jai; Chen, Ming-Huei; Thibord, Florian; McHugh, Caitlin; Surendran, Praveen; Blackwell, Thomas W; Brody, Jennifer A; Bhan, Arunoday; Chami, Nathalie; de Vries, Paul S; Ekunwe, Lynette; Heard-Costa, Nancy; Hobbs, Brian D; Manichaikul, Ani; Moon, Jee-Young; Preuss, Michael H; Ryan, Kathleen; Wang, Zhe; Wheeler, Marsha; Yanek, Lisa R; Abecasis, Goncalo R; Almasy, Laura; Beaty, Terri H; Becker, Lewis C; Blangero, John; Boerwinkle, Eric; Butterworth, Adam S; Choquet, Hélène; Correa, Adolfo; Curran, Joanne E; Faraday, Nauder; Fornage, Myriam; Glahn, David C; Hou, Lifang; Jorgenson, Eric; Kooperberg, Charles; Lewis, Joshua P; Lloyd-Jones, Donald M; Loos, Ruth J F; Min, Yuan-I; Mitchell, Braxton D; Morrison, Alanna C; Nickerson, Deborah A; North, Kari E; O'Connell, Jeffrey R; Pankratz, Nathan.

Hum Mol Genet ; 31(3): 347-361, 2022 02 03.

Artículo en Inglés | MEDLINE | ID: mdl-34553764

7.

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova, Anna V; McHugh, Caitlin P; Polfus, Linda M; Raffield, Laura M; Boorgula, Meher Preethi; Blackwell, Thomas W; Brody, Jennifer A; Broome, Jai; Chami, Nathalie; Chen, Ming-Huei; Conomos, Matthew P; Cox, Corey; Curran, Joanne E; Daya, Michelle; Ekunwe, Lynette; Glahn, David C; Heard-Costa, Nancy; Highland, Heather M; Hobbs, Brian D; Ilboudo, Yann; Jain, Deepti; Lange, Leslie A; Miller-Fleming, Tyne W; Min, Nancy; Moon, Jee-Young; Preuss, Michael H; Rosen, Jonathon; Ryan, Kathleen; Smith, Albert V; Sun, Quan; Surendran, Praveen; de Vries, Paul S; Walter, Klaudia; Wang, Zhe; Wheeler, Marsha; Yanek, Lisa R; Zhong, Xue; Abecasis, Goncalo R; Almasy, Laura; Barnes, Kathleen C; Beaty, Terri H; Becker, Lewis C; Blangero, John; Boerwinkle, Eric; Butterworth, Adam S; Chavan, Sameer; Cho, Michael H; Choquet, Hélène; Correa, Adolfo; Cox, Nancy.

Am J Hum Genet ; 108(10): 1836-1851, 2021 10 07.

Artículo en Inglés | MEDLINE | ID: mdl-34582791

8.

Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program.

Hu, Yao; Stilp, Adrienne M; McHugh, Caitlin P; Rao, Shuquan; Jain, Deepti; Zheng, Xiuwen; Lane, John; Méric de Bellefon, Sébastian; Raffield, Laura M; Chen, Ming-Huei; Yanek, Lisa R; Wheeler, Marsha; Yao, Yao; Ren, Chunyan; Broome, Jai; Moon, Jee-Young; de Vries, Paul S; Hobbs, Brian D; Sun, Quan; Surendran, Praveen; Brody, Jennifer A; Blackwell, Thomas W; Choquet, Hélène; Ryan, Kathleen; Duggirala, Ravindranath; Heard-Costa, Nancy; Wang, Zhe; Chami, Nathalie; Preuss, Michael H; Min, Nancy; Ekunwe, Lynette; Lange, Leslie A; Cushman, Mary; Faraday, Nauder; Curran, Joanne E; Almasy, Laura; Kundu, Kousik; Smith, Albert V; Gabriel, Stacey; Rotter, Jerome I; Fornage, Myriam; Lloyd-Jones, Donald M; Vasan, Ramachandran S; Smith, Nicholas L; North, Kari E; Boerwinkle, Eric; Becker, Lewis C; Lewis, Joshua P; Abecasis, Goncalo R; Hou, Lifang.

Am J Hum Genet ; 108(5): 874-893, 2021 05 06.

Artículo en Inglés | MEDLINE | ID: mdl-33887194

9.

Rapid, Phase-free Detection of Long Identity-by-Descent Segments Enables Effective Relationship Classification.

Seidman, Daniel N; Shenoy, Sushila A; Kim, Minsoo; Babu, Ramya; Woods, Ian G; Dyer, Thomas D; Lehman, Donna M; Curran, Joanne E; Duggirala, Ravindranath; Blangero, John; Williams, Amy L.

Am J Hum Genet ; 106(4): 453-466, 2020 04 02.

Artículo en Inglés | MEDLINE | ID: mdl-32197076

10.

Imaging local genetic influences on cortical folding.

Alexander-Bloch, Aaron F; Raznahan, Armin; Vandekar, Simon N; Seidlitz, Jakob; Lu, Zhixin; Mathias, Samuel R; Knowles, Emma; Mollon, Josephine; Rodrigue, Amanda; Curran, Joanne E; Görring, Harald H H; Satterthwaite, Theodore D; Gur, Raquel E; Bassett, Danielle S; Hoftman, Gil D; Pearlson, Godfrey; Shinohara, Russell T; Liu, Siyuan; Fox, Peter T; Almasy, Laura; Blangero, John; Glahn, David C.

Proc Natl Acad Sci U S A ; 117(13): 7430-7436, 2020 03 31.

Artículo en Inglés | MEDLINE | ID: mdl-32170019

11.

Rare coding variants in RCN3 are associated with blood pressure.

He, Karen Y; Kelly, Tanika N; Wang, Heming; Liang, Jingjing; Zhu, Luke; Cade, Brian E; Assimes, Themistocles L; Becker, Lewis C; Beitelshees, Amber L; Bielak, Lawrence F; Bress, Adam P; Brody, Jennifer A; Chang, Yen-Pei Christy; Chang, Yi-Cheng; de Vries, Paul S; Duggirala, Ravindranath; Fox, Ervin R; Franceschini, Nora; Furniss, Anna L; Gao, Yan; Guo, Xiuqing; Haessler, Jeffrey; Hung, Yi-Jen; Hwang, Shih-Jen; Irvin, Marguerite Ryan; Kalyani, Rita R; Liu, Ching-Ti; Liu, Chunyu; Martin, Lisa Warsinger; Montasser, May E; Muntner, Paul M; Mwasongwe, Stanford; Naseri, Take; Palmas, Walter; Reupena, Muagututi'a Sefuiva; Rice, Kenneth M; Sheu, Wayne H-H; Shimbo, Daichi; Smith, Jennifer A; Snively, Beverly M; Yanek, Lisa R; Zhao, Wei; Blangero, John; Boerwinkle, Eric; Chen, Yii-Der Ida; Correa, Adolfo; Cupples, L Adrienne; Curran, Joanne E; Fornage, Myriam; He, Jiang.

BMC Genomics ; 23(1): 148, 2022 Feb 19.

Artículo en Inglés | MEDLINE | ID: mdl-35183128

12.

Lipidomic profiling in the Strong Heart Study identified American Indians at risk of chronic kidney disease.

Zeng, Wenjie; Beyene, Habtamu B; Kuokkanen, Mikko; Miao, Guanhong; Magliano, Dianna J; Umans, Jason G; Franceschini, Nora; Cole, Shelley A; Michailidis, George; Lee, Elisa T; Howard, Barbara V; Fiehn, Oliver; Curran, Joanne E; Blangero, John; Meikle, Peter J; Zhao, Jinying.

Kidney Int ; 102(5): 1154-1166, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-35853479

13.

Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies.

Chen, Han; Huffman, Jennifer E; Brody, Jennifer A; Wang, Chaolong; Lee, Seunggeun; Li, Zilin; Gogarten, Stephanie M; Sofer, Tamar; Bielak, Lawrence F; Bis, Joshua C; Blangero, John; Bowler, Russell P; Cade, Brian E; Cho, Michael H; Correa, Adolfo; Curran, Joanne E; de Vries, Paul S; Glahn, David C; Guo, Xiuqing; Johnson, Andrew D; Kardia, Sharon; Kooperberg, Charles; Lewis, Joshua P; Liu, Xiaoming; Mathias, Rasika A; Mitchell, Braxton D; O'Connell, Jeffrey R; Peyser, Patricia A; Post, Wendy S; Reiner, Alex P; Rich, Stephen S; Rotter, Jerome I; Silverman, Edwin K; Smith, Jennifer A; Vasan, Ramachandran S; Wilson, James G; Yanek, Lisa R; Redline, Susan; Smith, Nicholas L; Boerwinkle, Eric; Borecki, Ingrid B; Cupples, L Adrienne; Laurie, Cathy C; Morrison, Alanna C; Rice, Kenneth M; Lin, Xihong.

Am J Hum Genet ; 104(2): 260-274, 2019 02 07.

Artículo en Inglés | MEDLINE | ID: mdl-30639324

14.

Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program.

Sarnowski, Chloé; Leong, Aaron; Raffield, Laura M; Wu, Peitao; de Vries, Paul S; DiCorpo, Daniel; Guo, Xiuqing; Xu, Huichun; Liu, Yongmei; Zheng, Xiuwen; Hu, Yao; Brody, Jennifer A; Goodarzi, Mark O; Hidalgo, Bertha A; Highland, Heather M; Jain, Deepti; Liu, Ching-Ti; Naik, Rakhi P; O'Connell, Jeffrey R; Perry, James A; Porneala, Bianca C; Selvin, Elizabeth; Wessel, Jennifer; Psaty, Bruce M; Curran, Joanne E; Peralta, Juan M; Blangero, John; Kooperberg, Charles; Mathias, Rasika; Johnson, Andrew D; Reiner, Alexander P; Mitchell, Braxton D; Cupples, L Adrienne; Vasan, Ramachandran S; Correa, Adolfo; Morrison, Alanna C; Boerwinkle, Eric; Rotter, Jerome I; Rich, Stephen S; Manning, Alisa K; Dupuis, Josée; Meigs, James B.

Am J Hum Genet ; 105(4): 706-718, 2019 10 03.

Artículo en Inglés | MEDLINE | ID: mdl-31564435

15.

Genetic determinants of metabolic biomarkers and their associations with cardiometabolic traits in Hispanic/Latino adolescents.

Kim, Daeeun; Justice, Anne E; Chittoor, Geetha; Blanco, Estela; Burrows, Raquel; Graff, Mariaelisa; Howard, Annie Green; Wang, Yujie; Rohde, Rebecca; Buchanan, Victoria L; Voruganti, V Saroja; Almeida, Marcio; Peralta, Juan; Lehman, Donna M; Curran, Joanne E; Comuzzie, Anthony G; Duggirala, Ravindranath; Blangero, John; Albala, Cecilia; Santos, José L; Angel, Bárbara; Lozoff, Betsy; Gahagan, Sheila; North, Kari E.

Pediatr Res ; 92(2): 563-571, 2022 08.

Artículo en Inglés | MEDLINE | ID: mdl-34645953

16.

Crossover interference and sex-specific genetic maps shape identical by descent sharing in close relatives.

Caballero, Madison; Seidman, Daniel N; Qiao, Ying; Sannerud, Jens; Dyer, Thomas D; Lehman, Donna M; Curran, Joanne E; Duggirala, Ravindranath; Blangero, John; Carmi, Shai; Williams, Amy L.

PLoS Genet ; 15(12): e1007979, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31860654

17.

Inferring Identical-by-Descent Sharing of Sample Ancestors Promotes High-Resolution Relative Detection.

Ramstetter, Monica D; Shenoy, Sushila A; Dyer, Thomas D; Lehman, Donna M; Curran, Joanne E; Duggirala, Ravindranath; Blangero, John; Mezey, Jason G; Williams, Amy L.

Am J Hum Genet ; 103(1): 30-44, 2018 07 05.

Artículo en Inglés | MEDLINE | ID: mdl-29937093

18.

Associations of cannabis use disorder with cognition, brain structure, and brain function in African Americans.

Koenis, Marinka M G; Durnez, Joke; Rodrigue, Amanda L; Mathias, Samuel R; Alexander-Bloch, Aaron F; Barrett, Jennifer A; Doucet, Gaelle E; Frangou, Sophia; Knowles, Emma E M; Mollon, Josephine; Denbow, Dominique; Aberizk, Katrina; Zatony, Molly; Janssen, Ronald J; Curran, Joanne E; Blangero, John; Poldrack, Russell A; Pearlson, Godfrey D; Glahn, David C.

Hum Brain Mapp ; 42(6): 1727-1741, 2021 04 15.

Artículo en Inglés | MEDLINE | ID: mdl-33340172

19.

Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia.

Sønderby, Ida E; Gústafsson, Ómar; Doan, Nhat Trung; Hibar, Derrek P; Martin-Brevet, Sandra; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Michael; Armstrong, Nicola J; Bernard, Manon; Blackburn, Nicholas; Blangero, John; Boomsma, Dorret I; Bralten, Janita; Brattbak, Hans-Richard; Brodaty, Henry; Brouwer, Rachel M; Bülow, Robin; Calhoun, Vince; Caspers, Svenja; Cavalleri, Gianpiero; Chen, Chi-Hua; Cichon, Sven; Ciufolini, Simone; Corvin, Aiden; Crespo-Facorro, Benedicto; Curran, Joanne E; Dale, Anders M; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J C; de Zubicaray, Greig I; de Zwarte, Sonja M C; Delanty, Norman; den Braber, Anouk; Desrivières, Sylvane; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Espeseth, Thomas; Fisher, Simon E; Franke, Barbara; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Glahn, David C; Grabe, Hans; Groenewold, Nynke A; Haavik, Jan.

Mol Psychiatry ; 25(3): 584-602, 2020 03.

Artículo en Inglés | MEDLINE | ID: mdl-30283035

20.

Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia.

Sønderby, Ida E; Gústafsson, Ómar; Doan, Nhat Trung; Hibar, Derrek P; Martin-Brevet, Sandra; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Michael; Armstrong, Nicola J; Bernard, Manon; Blackburn, Nicholas; Blangero, John; Boomsma, Dorret I; Bralten, Janita; Brattbak, Hans-Richard; Brodaty, Henry; Brouwer, Rachel M; Bülow, Robin; Calhoun, Vince; Caspers, Svenja; Cavalleri, Gianpiero; Chen, Chi-Hua; Cichon, Sven; Ciufolini, Simone; Corvin, Aiden; Crespo-Facorro, Benedicto; Curran, Joanne E; Dale, Anders M; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J C; de Zubicaray, Greig I; de Zwarte, Sonja M C; Delanty, Norman; den Braber, Anouk; Desrivières, Sylvane; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Espeseth, Thomas; Fisher, Simon E; Franke, Barbara; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Glahn, David C; Grabe, Hans; Groenewold, Nynke A; Haavik, Jan.

Mol Psychiatry ; 25(3): 692-695, 2020 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-30705424

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